Wednesday, February 28, 2007

A Fine Line

The reason that I am reluctant to advocate stem cell research is that I am in doubt of the human ability to use this technology in a constructive manner. With my grandmother suffering from Alzheimer's Disease, I want to believe in the bright future of stem cells, but how can we ever be sure that this technology will always be used to cure illnesses? Can legislative restrictions or moral appeals check the improper use of stem cell technology? I want to say yes, but unfortunately history shows that often times the mankind's biggest enemy is no one but themselves. It seems to me that we are often too optimistic about the medical benefits of stem cells that we neglect to think about worse scenarios.

In midst of such uncertainty, allowing stem cell research on a legislative level is like crossing a river that we cannot go back. Since the potential of stem cells are limitless, scientists or investors will often be tempted to cross fine moral lines in order to make a progress in areas of technology that are not particularly beneficial to the mankind--in the worst case, harmful. And by then, it will be extremly hard to stop such deviations.

I do not oppose stem cell research; however, I do believe that as a pioneering generation of stem cell research we must understand our responsibility in establishing ethical guidelines simultaneously with the research itself.

Tuesday, February 27, 2007

Ethical Economy

Whether it’s politics, religion, ethics, or science, there will always be a conflict of interest. One opinion cannot be considered right or wrong as it's one persons personal views on the subject. There will always be pros and cons, there will always be disagreement, and there will always be a counter-argument. So how to we move forward towards the future of this issue? There has to be a line, a balance if you will, that needs to be found. Perhaps a compromise can be made in terms of pursuing a solution to this problem, because if we continue arguing and bickering about the ethics of this issue, no solution will present itself. We will never get anything done.

In terms of pros and cons from the viewpoint of a pharmacologist, the pros definitely outweigh the cons. As we all know, the research that the stem cell scientists have already completed has yet to yield a successful therapy, yet we remain hopeful. In terms of the economy, the search for a successful stem cell therapy procedure will automatically boost our country’s financial success 10 fold. Things like equipment expenditures and proposed capital will increase the economic activity throughout the industry, and throughout the country. Jobs will be created, and royalty payments due to state and local revenues will continue to add to our economy. The economic benefits to stem cell research are endless; we just have to put some energy into the research instead of the argument about ethics.
Other things that the country will gain from successful therapies are: lower health care costs, less job hours lost due to the diseases directly associated with these therapies, and more importantly, less premature deaths due to the main diseases that can and will be treated by stem cell therapies. The amount of animal testing will also be reduced because of the fact that embryos are a far better example of the human’s impact profile. Since we will be ultimately using these successful therapies on humans, the use of lab animals for inhumane animal testing will decrease exponentially.
As you can see, my viewpoint presented many positive benefits due to stem cell research. I can assure you that my views are, in a way, narrow-minded, and don’t take into account the other viewpoints people might bring up. In researching for the part of pharmacologist, the only downside that I came across would be spending all this money and not gaining a successful therapy. And as this is the only downside economically, I would say, let's get going!

Monday, February 26, 2007

Therapeutic Cloning

Most bioethicists appear to have much stronger moral objections to the idea of obtaining embryonic stem cells through therapeutic cloning than to the idea of obtaining them from left-over IVF embryos. Clearly the first option would be better from a medical standpoint because the resulting stem cells would be less likely to be rejected by the patient's immune system, since the genetic makeup of the stem cells would be identical to that of the patient (being a clone), while with the second option that rejection would certainly be likely, and thus a major obstacle in treatment.

The bioethicists who oppose therapeutic cloning claim that it is morally wrong because a human life is being created solely for the purpose of obtaining stem cells and then it is destroyed (quite different from a left-over embryo that would die anyway). But is this embryo really a human life? It might seem like a dumb question, because if everything is done correctly it would develop into a clone human being (if the technology was perfected). But think about how it is created: it isn't conceived naturally from a sperm and an egg, rather it is an egg with artificially inserted genetic material that is 'stimulated' to divide and form an embryo. If a human life is sacred, and for that reason it deserves respect, how can this cloned embryo be sacred if it is produced completely artificially, asexually in fact, and its really the scientist that's playing God to create it. Could it be considered a non-sacred, immitation form of life that is developed for medical purposes entirely, and thus does not deserve the respect and dignity of human life as we know it? Could then it be morally justified to create this embryo in order to destroy it, unlike what some bioethicists contend?

Potential

An obvious argument for the affirmative is that fertilized embryos created in petri dishes are likely to be thrown out anyway, making them guilt-free usable for embryonic stem cell research. The counter argument by Right-to-Life advocates states that these embryos should not be thrown away, but given to surrogate mothers. They say that these embryos have rights due to their potential to becoming a human being. I would like to address this argument.

Fertilized embryos cannot develop into living fetuses if they remain in a petri dish. A scientist must actively implant the embryo into a womb to start the growth; the embryo is essentially dependent on the scientist to become a human. Similarly, the embryo is dependant on the scientist to become an organ. Without a trigger, it will not naturally grow into a liver, brain, kidney, pancreas, etc. The dependance, from the "perspective" of the embryo, makes it equally likely to develop into a human as it is to develop into a liver.

This is unlike an embryo conceived in the womb because, assuming a healthy pregnancy, this embryo can only become one thing - a human.

If something is equally likely to develop into many things, how can it be considered a specific one of those things? It can be a liver and a human, then it is neither. Therefore, I believe it is not a human but a manipulatable object that may be used for research.

Attack me if you must.

Patents

I recently read an article in the European Wall Street Journal covering the Microsoft vs. AT&T patent case. I couldn't find a link to the specific article (because I read the article in print... how old-fashioned) but essentially, the case is arguing a technicality in patent law. AT&T holds a patent on a certain type of software (voice compression technology, if you're interested). Microsoft says it would be okay to ship a "golden disk" which has a copy of that patented software on it overseas, where it could be replicated. Those duplicate disks could be used to install the software on computers manufactured outside the US then redistributed to the US and elsewhere. The dispute is in the fact that Microsoft contends the "component" which has been patented is the physical disk, whereas AT&T contends that the "component" is the software itself, no matter what medium it's on. What struck my interest was when the article stated "This issue could have implications for other high-tech products that can easily be duplicated, such as bioengineered organisms." Technically an idea or a principle can't be patented - but is source code an idea or a component? The law is going to have a hard time keeping up with new technology and intellectual property issues surrounding it. I honestly don't know enough about the technology behind stem cell research to directly apply this to our discussion, but I thought it was an interesting concept.

Thursday, February 15, 2007

Embryos are Humans Too

As a representative from the right to life side of this issue I would like to raise several critical points regarding embryonic stem cells. First, it is important to actually think about what you are doing when you kill an embryo. You are in effect killing a human being that is slowly moving forward in the standard progression we all followed to become who we are today. Would you kill a baby in the third trimester of pregnancy? Probably not. So what makes an embryo any different. Is it consciousness? Most certainly not because we treat a mentally retarded person as an equal human being so why not an embryo? Is it the physical attributes? Of course not because physical deformities in adults do not prevent us from thinking of them as human beings. So I ask...why is an embryo not a human being and how is killing an embryo for its stem cells not murder?

To further drive this point home, I would like to ask you why spend the money to consciously murder embryos when we have new technology at our fingertips that provides the equal potential as embryonic stem cells? Specifically, a recent report published by "Nature biotechnology" cites the extraordinarily promising results with amniotic stem cells. You can find an abstract from this study on PubMed.gov under the name Isolation of amniotic stem cell lines with potential for therapy. This study demonstrated that amniotic stem cells are multi-potent and were able to differentiate into cells types that represented all germ layers. These cells are easy to grow and like embryonic stem cells are non-tumorogenic and resist telomere erosion. If there exist such cells as these that do not require the murder of human beings then why not focus our resources on these. Federal funding should not be focused towards murder but the proactive solution such as amniotic stem cells.

Tuesday, February 13, 2007

Superhumans?

"Whereas tissue engineering and bioartificial organs have remained relatively uncontested, xenotransplantation and, in particular, therapeutic cloning and embryonic stem cell research have given rise to heated debates in Europe and in the United States. What some interpreted as a "medical revolution," others saw as an attempt to create "superhumans," as a revival of Nazi eugenics in new clothes, or as a potential public health disaster."
[This was stated by Herbert Gotweiss in his article "Stem Cell Policies in the United States and in Germany: Between Bioethics and Regulation"]

It sounds ridiculous to many, but the development of a superhuman race as a result of therapeutic cloning, etc. is a relevant possibility.

With little, if any, funding for stem cell research coming from the federal government, a significant portion of money comes from venture capitalists hoping to profit from the potential development of life saving and improving techniques.

If these techniques become viable, they will be expensive, and therefore only accessible to the wealthier classes. As recipients of these treatments reproduce with each other (as people in similar segments of society often do) a new, more genetically "perfect" (I use that term loosely) race may emerge, one that is -- more capable? more qualified for jobs? Could this perpetuate economic divisions already present in society today, or worse?

What do people think about this? Is it ridiculous, unfounded science fiction or a plausible scenario? What could the implications be?